Lichten G D, Pomeranz J R, Chester C S, Kark E C
J Am Acad Dermatol. 1980 May;2(5):388-92. doi: 10.1016/s0190-9622(80)80361-6.
This report describes a case of secondary syphilis presenting with an atypical cutaneous eruption and acute spastic quadriparesis. The etiology of the cutaneous and neurologic manifestations was obscure until cerebrospinal fluid (CSF) studies revealed pleocytosis, elevated protein, and a positive CSF, VDRL, and fluorescent treponemal antibody (FTA). These findings, correlated with the histologic presence of plasma cells in the dermal infiltrate, indicated secondary syphilis with acute syphilitic meningitis as the cause of the patient's illness. Therapy with intravenous penicillin, 20 million units daily for 3 weeks, resulted in almost complete recovery.
本报告描述了一例二期梅毒病例，该病例表现为非典型皮肤疹和急性痉挛性四肢瘫。在脑脊液（CSF）研究显示细胞增多、蛋白升高以及脑脊液性病研究实验室玻片试验（VDRL）和荧光密螺旋体抗体（FTA）呈阳性之前，皮肤和神经表现的病因一直不明。这些发现与真皮浸润中浆细胞的组织学存在相关，表明二期梅毒合并急性梅毒性脑膜炎是患者疾病的病因。采用每日静脉注射青霉素2000万单位，持续3周的治疗，使患者几乎完全康复。
