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意大利塞韦索的人类急性二噁英暴露事件。

Acute human exposure to TCDD in Seveso, Italy.

作者信息

Reggiani G

出版信息

J Toxicol Environ Health. 1980 Jan;6(1):27-43. doi: 10.1080/15287398009529828.

DOI:10.1080/15287398009529828
PMID:7381973
Abstract

The children and adults who suffered injuries after exposure to chemicals that escaped in July 1976 from a reactor during the production of trichlorophenol is Seveso, Italy, have been repeatedly examined by a medical commission appointed by the judge holding the legal inquest. All patients suffered burnlike skin lesions and all but two recovered without residual effects. Chloracne occurred in 12 of these cases; it was mild in almost all and has now disappeared. Systemic functions were repeatedly evaluated in all cases and no evidence of visceral lesions was obtained. Immunocapability was normal and chromosome aberrations were within the normal range.

摘要

1976年7月,意大利塞韦索一家生产三氯苯酚的工厂发生反应堆化学品泄漏事件,之后受伤的儿童和成人接受了负责该法律调查的法官指定的医学委员会的多次检查。所有患者都有类似烧伤的皮肤损伤,除两人外,其他人都已康复,没有留下后遗症。其中12例出现氯痤疮;几乎所有病例症状都较轻,现在已经消失。对所有病例的全身功能进行了多次评估,未发现内脏损伤迹象。免疫能力正常,染色体畸变在正常范围内。

相似文献

1
Acute human exposure to TCDD in Seveso, Italy.意大利塞韦索的人类急性二噁英暴露事件。
J Toxicol Environ Health. 1980 Jan;6(1):27-43. doi: 10.1080/15287398009529828.
2
TCDD poisoning at Seveso.塞韦索的二噁英中毒事件。
Biomedicine. 1977 Feb;26(1):28-9.
3
Follow-up of subjects who developed chloracne following TCDD exposure at Seveso.对在塞韦索因接触2,3,7,8-四氯二苯并对二恶英而患氯痤疮的受试者进行随访。
Am J Ind Med. 1989;16(2):119-25. doi: 10.1002/ajim.4700160203.
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Medical survey techniques in the Seveso TCDD exposure.塞韦索地区二噁英暴露中的医学调查技术
J Appl Toxicol. 1981 Dec;1(6):323-31. doi: 10.1002/jat.2550010611.
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Considerations on the epidemiology of the Seveso accident.
Toxicol Eur Res. 1981 Jan;3(1):9-16.
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Medical problems raised by the TCDD contamination in Seveso, Italy.
Arch Toxicol. 1978 Jun 16;40(3):161-88. doi: 10.1007/BF00364649.
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Seveso after five years.塞韦索事件五年后。
Lancet. 1981 Oct 3;2(8249):731-2.
8
Chloracne following environmental contamination by TCDD in Seveso, Italy.意大利塞韦索因二噁英环境污染导致的氯痤疮。
Int J Epidemiol. 1981 Jun;10(2):135-43. doi: 10.1093/ije/10.2.135.
9
Health status and plasma dioxin levels in chloracne cases 20 years after the Seveso, Italy accident.意大利塞韦索事故20年后氯痤疮患者的健康状况和血浆二恶英水平。
Br J Dermatol. 2005 Mar;152(3):459-65. doi: 10.1111/j.1365-2133.2005.06444.x.
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Cutaneous manifestations of tetrachlorodibenzo-p-dioxin in children and adolescents. Follow-up 10 years after the Seveso, Italy, accident.
J Am Acad Dermatol. 1988 Nov;19(5 Pt 1):812-9. doi: 10.1016/s0190-9622(88)70238-8.

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