Wilson R, Lovejoy F H, Jaeger R J, Landrigan P L
JAMA. 1980 Jul 11;244(2):148-50.
Two children and 29 of 31 crew members aboard a grain freighter became acutely ill after inhaling the toxic fumigant phosphine; one child died. Predominant symptoms were headache, fatigue, nausea, vomiting, cough, and shortness of breath. Abnormal physical findings included jaundice, paresthesias, ataxia, intention tremor, and diplopia. Focal myocardial infiltration with necrosis, pulmonary edema, and widespread small-vessel injury were found at postmortem examination of the dead child. The surviving child showed ECG and echocardiographic evidence of myocardial injury and transient elevation of the MB fraction of serum creatinine phosphokinase. Illness was significantly associated with living or working amidships or on the forward deck areas of the vessel. Phosphine gas was found to have escaped from the holds through a cable housing located near the midships ventilation intake and around hatch covers on the forward deck. The outbreak illustrates the hazards associated with shipboard fumigation.
一艘谷物货船上的两名儿童和31名船员中的29人在吸入有毒熏蒸剂磷化氢后急性发病；一名儿童死亡。主要症状为头痛、疲劳、恶心、呕吐、咳嗽和呼吸急促。异常体征包括黄疸、感觉异常、共济失调、意向性震颤和复视。对死亡儿童进行尸检时发现有局灶性心肌浸润伴坏死、肺水肿和广泛的小血管损伤。幸存儿童的心电图和超声心动图显示有心肌损伤证据，血清肌酸磷酸激酶MB分数短暂升高。发病与在船中部或前甲板区域生活或工作密切相关。发现磷化氢气体通过位于船中部通风口附近的电缆槽以及前甲板舱口盖周围从货舱逸出。此次疫情说明了船上熏蒸带来的危害。
