苯肼对红细胞中δ-氨基乙酰丙酸脱水酶的影响。
Effect of phenylhydrazine on delta-aminolevulinic acid dehydratase in red blood cells.
作者信息
Abdulla M, Svensson S
出版信息
Enzyme. 1978;23(3):164-9. doi: 10.1159/000458571.
PMID:738253
Abstract
Delta-aminolevulinic acid dehydratase activity was measured in the blood of rats poisoned by successive injections of phenylhydrazine (1 ml, 35 mmol). After 5 days of successive injections, more than 90% of the circulating blood cells consisted of reticulocytes and the enzyme activity also increased successively and reached a maximum corresponding to the number of reticulocytes. Thus delta-aminolevulinic acid dehydratase activity measured in the peripheral blood is mainly due to the percentage of circulating reticulocytes.
摘要
通过连续注射苯肼（1毫升，35毫摩尔）使大鼠中毒，然后测定其血液中的δ-氨基乙酰丙酸脱水酶活性。连续注射5天后，循环血液细胞中90%以上为网织红细胞，且该酶活性也相继升高，并达到与网织红细胞数量相对应的最大值。因此，在外周血中测得的δ-氨基乙酰丙酸脱水酶活性主要归因于循环中网织红细胞的百分比。
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