Kamalam A, Thambiah A S
Mycopathologia. 1980 May 1;71(1):45-51. doi: 10.1007/BF00625314.
A study of Tinea capitis in Outpatient Clinic, Skin Department, Government General Hospital, Madras during a three year period from November, 1973 to October, 1976, has shown a gradual increase in incidence of 3.56%, 5.09% and 6.25% respectively. Findings suggest that Tinea capitis is endemic in South India. Male children were more commonly affected than female children and the age groups chiefly affected were between 5 and 10 years. A considerably number of adults were also affected. The disease showed no correlation to environmental temperature, humidity and rainfall but was correlated to all types of mycoses and total incidence of mycoses. Among 357 isolates, Trichophyton violaceum was the commonest in 264 (73.94%) and T. tonsurans was the next common in 47 (13.16%). The other agents were T. rubrum in 30 (8.4%), T. mentagrophytes in 11 (3.08%) and T. simii in 5 (1.4%). Noninflammatory lesions were more common than inflammatory lesions and both were produced by T. violaceum and T. tonsurans, suggesting strain differences in pathogenesis. Treatment with oral griseofulvin was satisfactory in all but had to be discontinued in 4 patients due to side effects.
对马德拉斯政府总医院皮肤科门诊在1973年11月至1976年10月这三年期间头癣的一项研究表明,发病率分别逐年上升,为3.56%、5.09%和6.25%。研究结果表明头癣在南印度呈地方流行性。男童比女童更易受感染,主要受影响的年龄组在5至10岁之间。也有相当数量的成年人受到感染。该疾病与环境温度、湿度和降雨量无关,但与所有类型的霉菌病及霉菌病总发病率相关。在357株分离菌株中,紫色毛癣菌最为常见,有264株(73.94%),断发毛癣菌次之,有47株(13.16%)。其他病原体为红色毛癣菌30株(8.4%)、须癣毛癣菌11株(3.08%)和石膏样毛癣菌5株(1.4%)。非炎性损害比炎性损害更常见,两者均由紫色毛癣菌和断发毛癣菌引起,提示发病机制存在菌株差异。口服灰黄霉素治疗除4例因副作用停药外,对所有患者均有效。