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Voltage-clamp analysis of the sodium and potassium currents in skeletal muscle fibres treated with 4-aminopyridine.

作者信息

Molgó J

出版信息

Experientia. 1978 Oct 15;34(10):1275-9. doi: 10.1007/BF01981414.

DOI:10.1007/BF01981414
PMID:738393
Abstract

External application of low concentrations of 4-aminopyridine blocks potassium currents without affecting sodium currents in pieces of single frog skeletal muscle fibres. The blockade of potassium currents was voltage-dependent, being partially relieved on depolarization.

摘要

相似文献

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本文引用的文献

1
The influence of potassium and chloride ions on the membrane potential of single muscle fibres.钾离子和氯离子对单根肌纤维膜电位的影响。
J Physiol. 1959 Oct;148(1):127-60. doi: 10.1113/jphysiol.1959.sp006278.
2
The effect of the tetraethylammonium ion on the delayed currents of frog skeletal muscle.四乙铵离子对青蛙骨骼肌延迟电流的影响。
J Physiol. 1970 Jul;209(1):209-29. doi: 10.1113/jphysiol.1970.sp009163.
3
The actions of tetraethylammonium ions on potassium fluxes in frog sartorius muscle.四乙铵离子对蛙缝匠肌钾离子通量的作用。
猫用4-氨基吡啶有效治疗维拉帕米中毒
J Clin Invest. 1984 May;73(5):1291-6. doi: 10.1172/JCI111331.
4
Relation between action potential duration and mechanical activity on rat diaphragm fibers. Effects of 3,4-diaminopyridine and tetraethylammonium.大鼠膈肌纤维动作电位持续时间与机械活动之间的关系。3,4-二氨基吡啶和四乙铵的作用
Pflugers Arch. 1987 Nov;410(4-5):394-400. doi: 10.1007/BF00586516.
J Pharmacol Exp Ther. 1970 Apr;172(2):230-8.
4
Proceedings: Selective inhibition of potassium current in the giant axon of the cockroach.论文集：蟑螂巨轴突中钾电流的选择性抑制
J Physiol. 1974 Oct;242(2):90P-91P.
5
Ionic pores, gates, and gating currents.离子孔道、门控通道和门控电流。
Q Rev Biophys. 1974 May;7(2):179-210. doi: 10.1017/s0033583500001402.
6
Chemicals as tools in the study of excitable membranes.化学物质作为研究可兴奋膜的工具。
Physiol Rev. 1974 Oct;54(4):813-89. doi: 10.1152/physrev.1974.54.4.813.
7
Synaptic transmission in squid giant synapse after potassium conductance blockage with external 3- and 4-aminopyridine.用外部3-氨基吡啶和4-氨基吡啶阻断钾电导后乌贼巨大突触中的突触传递。
Biophys J. 1976 Jan;16(1):83-6. doi: 10.1016/S0006-3495(76)85664-0.
8
Interactions of aminopyridines with potassium channels of squid axon membranes.氨基吡啶与鱿鱼轴突膜钾通道的相互作用。
Biophys J. 1976 Jan;16(1):77-81. doi: 10.1016/S0006-3495(76)85663-9.
9
Block of potassium channels of the nodal membrane by 4-aminopyridine and its partial removal on depolarization.4-氨基吡啶对结区膜钾通道的阻断及其在去极化时的部分解除。
Pflugers Arch. 1976 Nov 30;367(1):77-87. doi: 10.1007/BF00583659.
10
An improved vaseline gap voltage clamp for skeletal muscle fibers.一种改进的用于骨骼肌纤维的凡士林间隙电压钳。
J Gen Physiol. 1976 Mar;67(3):265-93. doi: 10.1085/jgp.67.3.265.