Böhme H R, Baehnisch G
Pharmazie. 1980 Jan;35(1):26-9.
Only some few systematic studies have appeared in the literature relative to the interference of drugs with clinico-chemical screening and rapid tests. This question is dealt with in the light of in vitro and in vivo investigations of the interference of selected drugs with screening test reagents produced in the G.D.R. In contrast to speculations in the secondary literature, a practice-relevant interference of the drugs under investigation with the test procedures was an exception. In this sense, our following findings are of importance: --inhibitory action of ascorbic acid and sodium fluoride on the demonstration of glucose by Biophan G, --false positive indication of Biophan PAS in case of high concentrations of sulphamerazine, --interference of ascorbic acid with the Biophan P test.
关于药物对临床化学筛查和快速检测的干扰，文献中仅有少数一些系统性研究。本文根据对民主德国生产的筛查测试试剂，所选药物干扰的体外和体内研究来探讨这个问题。与二次文献中的推测相反，所研究药物对测试程序产生与实际应用相关的干扰是个例外。从这个意义上说，我们的以下发现很重要：——抗坏血酸和氟化钠对Biophan G检测葡萄糖的抑制作用，——磺胺甲基嘧啶浓度高时Biophan PAS出现假阳性指示，——抗坏血酸对Biophan P检测的干扰。
