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在由真菌半乳甘露聚糖肽诱导的兔高脂血症模型上。

On a rabbit hyperlipemia induced by a fungic galactomannane peptide.

作者信息

Cambier D, Labbé J P

出版信息

Experientia. 1978 Oct 15;34(10):1384-5. doi: 10.1007/BF01981490.

DOI:10.1007/BF01981490
PMID:738437
Abstract

I.v. injection into rabbits of a fungic galactomannane peptide isolated from the culture medium of Aspergillus oryzae induced the apparition, 20 h later, of an hypertriglyceridemia, with a concomittant decrease of about 70% of the post-heparin lipoprotein lipase activity. The same effect had been obtained earlier with a carbohydrate-rich fraction purified from a crude papain preparation. The 2 fractions are compared.

摘要

将从米曲霉培养基中分离出的真菌半乳甘露聚糖肽静脉注射到兔子体内,20小时后出现高甘油三酯血症,同时肝素后脂蛋白脂肪酶活性降低约70%。早些时候,从粗木瓜蛋白酶制剂中纯化出的富含碳水化合物的部分也得到了同样的效果。对这两个部分进行了比较。

相似文献

1
On a rabbit hyperlipemia induced by a fungic galactomannane peptide.在由真菌半乳甘露聚糖肽诱导的兔高脂血症模型上。
Experientia. 1978 Oct 15;34(10):1384-5. doi: 10.1007/BF01981490.
2
Induction of hyperlipemia by carbohydrate-rich fractions isolated from crude papain.从粗木瓜蛋白酶中分离出的富含碳水化合物的组分诱导高脂血症
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Biochim Biophys Acta. 1985 Dec 4;837(3):262-70. doi: 10.1016/0005-2760(85)90049-9.

本文引用的文献

1
Corticotropininduced hyperlipemia in rabbits.促肾上腺皮质激素诱导的家兔高脂血症
Proc Soc Exp Biol Med. 1962 Nov;111:257-61.
2
Fat mobilization and hyperlipemia from pituitary extracts in rabbits.垂体提取物对兔脂肪动员和高脂血症的影响
Am J Physiol. 1961 Apr;200:841-6. doi: 10.1152/ajplegacy.1961.200.4.841.
3
Inhibition of lipoprotein lipase activity following injection of pituitary extracts into rabbits.向兔子注射垂体提取物后脂蛋白脂肪酶活性的抑制作用。
J Exp Med. 1960 Jul 1;112(1):1-14. doi: 10.1084/jem.112.1.1.
4
Lipemia in the rabbit following injection of pituitary extract.注射垂体提取物后兔子出现脂血。
Proc Soc Exp Biol Med. 1958 Oct;99(1):146-50. doi: 10.3181/00379727-99-24276.
5
Chromatography of polypeptides and proteins on hydroxyapatite columns.多肽和蛋白质在羟基磷灰石柱上的色谱分析。
Biochim Biophys Acta. 1968 Aug 13;160(3):301-10. doi: 10.1016/0005-2795(68)90203-1.
6
[The natural inhibitor of the clearing factor].[清除因子的天然抑制剂]
Bull Acad Natl Med. 1967 Oct 17;151(25):521-4.
7
[Isolation of fractions having aminopeptidase activity (EC 3.4.1.1) (arylamidase) from culture medium of Aspergillus oryzae].
Biochimie. 1974;56(6-7):839-44. doi: 10.1016/s0300-9084(74)80505-5.
8
[Study of serum and urinary modifications in young rabbits provoked by intravenous injections of crude papain].[静脉注射粗木瓜蛋白酶对幼兔血清和尿液影响的研究]
Bull Soc Chim Biol (Paris). 1969 Oct;51(5):891-907.
9
"Lipolipin": a glycoprotein inhibitor of postheparin plasma lipoprotein lipase.“脂联素”:一种肝素后血浆脂蛋白脂肪酶的糖蛋白抑制剂。
Adv Exp Med Biol. 1975;52:281-8. doi: 10.1007/978-1-4684-0946-8_25.
10
Induction of hyperlipemia by carbohydrate-rich fractions isolated from crude papain.从粗木瓜蛋白酶中分离出的富含碳水化合物的组分诱导高脂血症
Biomedicine. 1978 May-Jun;28(3):175-80.