Russell E J, George A E, Kricheff I I, Budzilovich G
Radiology. 1980 Jun;135(3):673-82. doi: 10.1148/radiology.135.3.7384454.
While most intracranial meningiomas have characteristic computed tomographic (CT) findings, a significant number produce atypical images that may lead to a spurious histopathological diagnosis. The authors reviewed 131 consecutive, previously untreated cases of meningioma, all confirmed pathologically. Nine cases (7%) were misdiagnosed initially as malignant lesions based on CT findings alone. Features such as irregular areas of nonenhancing mass and well defined regions of persistent low density were the reasons for misdiagnosis. Close correlation with pathological findings of tumor necrosis, hemorrhage, scarring, and cystic change was noted. An unexpectedly high incidence of necrosis in untreated meningioma is noteworthy.
虽然大多数颅内脑膜瘤具有特征性的计算机断层扫描（CT）表现，但仍有相当数量的病例呈现非典型图像，这可能导致错误的组织病理学诊断。作者回顾了131例连续的、未经治疗的脑膜瘤病例，所有病例均经病理证实。其中9例（7%）最初仅根据CT表现被误诊为恶性病变。非强化肿块的不规则区域以及持续低密度的清晰界定区域等特征是误诊的原因。注意到这些特征与肿瘤坏死、出血、瘢痕形成和囊性变的病理结果密切相关。未经治疗的脑膜瘤中坏死发生率意外地高，这一点值得关注。
