Department of Neurosurgery, Sun Yat-sen University Cancer Center, No, 651, Dong Feng Road E., Guang-zhou 510060, PR China.
World J Surg Oncol. 2012 Jan 12;10:10. doi: 10.1186/1477-7819-10-10.
Both intraparenchymal papillary meningioma and papillary meningioma with cyst formation of brainstem have never been reported. The authors present an extremely rare case of patient with intraparenchymal papillary meningioma of brainstem. A 23-year-old Chinese male presented with a 4-month history of progressive left upper limb and facial nerve palsy. Magnetic resonance imaging revealed a cystic-solid, heterogeneously enhancing mass in pons and right cerebral peduncle with no dural attachment. The tumor was totally removed via subtemporal approach. During surgery, the lesion was found to be completely intraparenchymal. Histological and immunohistochemical examinations were compatible with the diagnosis of papillary meningioma. The lesion recurred nine months after primary surgery, a second surgery followed by radiotherapy was performed. Till to now (nearly 2 years after the treatment), the patient is tumor free survival. Intraparenchymal meningioma of brainstem with cystic formation is very rare, however, it should be considered as a differential diagnosis of a brainstem neoplasm. The present case strongly recommended that postoperative radiotherapy was essential for the patients with papillary meningiomas.
脑实质内乳头型脑膜瘤和伴有脑干部位囊形成的乳头型脑膜瘤均未曾报道。作者报告了一例极为罕见的脑干部位脑实质内乳头型脑膜瘤患者。一名 23 岁的中国男性,因左上肢和面神经进行性瘫痪 4 个月就诊。磁共振成像显示桥脑和右侧大脑脚存在囊实性、不均匀强化肿块,无硬脑膜附着。通过颞下入路全切肿瘤。术中发现病变完全位于脑实质内。组织学和免疫组织化学检查符合乳头型脑膜瘤的诊断。初次手术后 9 个月肿瘤复发,进行了第二次手术和放疗。至今(治疗后近 2 年),患者无肿瘤生存。脑实质内伴有囊形成的脑膜瘤非常罕见,但应作为脑干部位肿瘤的鉴别诊断之一。本病例强烈提示,对于乳头型脑膜瘤患者,术后放疗是必要的。