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解剖无效腔对潮气量和呼气末肺容积的依赖性:细支气管张力的动态行为与稳定(作者译)

[Dependence of the anatomical dead space on the tidal volume and on the endexpiratory lung volume: dynamic behaviour and stabilization of the bronchiolar tone (author's transl)].

作者信息

Barnikol W K, Diether K

出版信息

Respiration. 1980;39(1):8-9. doi: 10.1159/000194192.

DOI:10.1159/000194192
PMID:7384655
Abstract

The anatomical dead space was measured in dependence on the tidal volume and on the endexpiratory lung volume (respiratory level). A new method, the method of dead air plateau, was employed. The dead space increases with tidal volume (4 ml/100 ml). It is not dependent on the respiratory level. This was also directly shown in breathing manoeuvres changing the respiratory level rectangularly. In such manoeuvres a stabilization process can be seen. The same results give resistance measurements (oscillatory method). Values are taken in the endinspiratory state. This corresponds to the dead space volume. The 70% time of the stabilization reaction can be estimated, it is 20 sec. Taking this time into account, it is well understood that dead space volume is dependent on the tidal volume, but not dependent on the respiratory level. This time also makes evident that the often mentioned history of lung parameters lasts approximately 20 sec. The biological significance of the stabilization is discussed.

摘要

根据潮气量和呼气末肺容积(呼吸水平)测量解剖无效腔。采用了一种新方法,即死腔平台法。无效腔随潮气量增加(4 ml/100 ml)。它不依赖于呼吸水平。这也在以矩形方式改变呼吸水平的呼吸动作中直接得到了体现。在这种动作中可以看到一个稳定过程。阻力测量(振荡法)也得到了相同的结果。在吸气末状态取值。这与无效腔容积相对应。可以估算出稳定反应的70%时间为20秒。考虑到这个时间,很容易理解无效腔容积依赖于潮气量,而不依赖于呼吸水平。这个时间也表明,经常提到的肺参数变化过程大约持续20秒。文中讨论了稳定作用的生物学意义。

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