Sikora K, Anand B S, Truelove S C, Ciclitira P J, Offord R E
Lancet. 1976 Aug 21;2(7982):389-91. doi: 10.1016/s0140-6736(76)92406-5.
Peripheral-blood lymphocytes from patients with coeliac disease showed a marked increase in D.N.A. synthesis after incubation in vitro with a subfraction of gluten. Lymphocytes from control patients showed no increased D.N.A. synthesis under the same conditions. The possible use of this specific lymphocyte-stimulation assay as a screening test for coeliac disease is discussed.