Klein H G, Faltz L L, McIntosh C L, Appelbaum F R, Deisseroth A B, Holland P V
Transfusion. 1980 May-Jun;20(3):354-7. doi: 10.1046/j.1537-2995.1980.20380214906.x.
Cold agglutinins are a potential danger to patients who must be subjected to hypothermia. A patient with a cold agglutinin of moderate titer but broad thermal amplitude was to undergo hypothermia during aortic valve replacement. He was managed preoperatively with an eight-liter plasma exchange by continuous-flow centrifugation to remove the cold agglutinin. There were no adverse effects during or after hypothermia.
冷凝集素对必须接受低温治疗的患者构成潜在危险。一名冷凝集素滴度中等但热幅较宽的患者在主动脉瓣置换期间要接受低温治疗。术前通过连续流动离心进行了八升血浆置换以去除冷凝集素。低温治疗期间及之后均未出现不良反应。