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[肾上腺切除术后大鼠组织有丝分裂的昼夜节律及细胞更新率]

[Diurnal rhythm of mitoses and rate of cell renewal in rat tissues following adrenalectomy].

作者信息

Mamontov S G, Ivanova L N, Zakharov V B

出版信息

Tsitologiia. 1980 Feb;22(2):168-75.

PMID:7385360
Abstract

Numbers of mitoses and of colchicine mitoses, and the duration of mitosis in corneal and tongue epithelium as well as in hepatocytes of intact and adrenalectomized rats have been studied in dynamics within 24 hours. In the control animals, the 24 hours rhythm of mitotic activity and the duration of mitosis were established. The length of mitosis falls during the high rate mitotic activity to increase when the number of dividing cells is reduced. Adrenalectomy results in decreasing the amplitude of mitotic activity fluctuations and in diminishing the amount cells entering mitosis during the 24 hours period. The rate of physiological regeneration in tissues of adrenalectomized animals is reduced. Different sensibilities of investigated tissues to adrenal cortex hormones deficiency have been revealed.

摘要

研究了完整大鼠和肾上腺切除大鼠的角膜、舌上皮以及肝细胞在24小时内有丝分裂和秋水仙素诱导有丝分裂的数量,以及有丝分裂的持续时间。在对照动物中,确定了有丝分裂活动的24小时节律和有丝分裂的持续时间。有丝分裂的持续时间在有丝分裂活动率高时缩短,而在分裂细胞数量减少时增加。肾上腺切除术导致有丝分裂活动波动幅度减小,以及24小时内进入有丝分裂的细胞数量减少。肾上腺切除动物组织中的生理再生速率降低。已揭示所研究组织对肾上腺皮质激素缺乏的不同敏感性。

相似文献

1
[Diurnal rhythm of mitoses and rate of cell renewal in rat tissues following adrenalectomy].[肾上腺切除术后大鼠组织有丝分裂的昼夜节律及细胞更新率]
Tsitologiia. 1980 Feb;22(2):168-75.
2
[Circadian rhythm of the number of DNA-syns and following adrenalectomy].
Biull Eksp Biol Med. 1977 Apr;83(4):479-81.
3
[Circadian rhythm of mitoses and number of cells synthesizing DNA following adrenalectomy in mice].[小鼠肾上腺切除术后有丝分裂的昼夜节律及合成DNA的细胞数量]
Biull Eksp Biol Med. 1976 Jun;81(6):740-2.
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[Circardian rhythm of mitoses in the epithelium of the cornea after splenectomy].[脾切除术后角膜上皮有丝分裂的昼夜节律]
Biull Eksp Biol Med. 1979 Jun;87(6):594-5.
5
[Effect of stressors on the mitotic regime and certain cell cycle events in the corneal epithelium of adrenalectomized rats].
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Tsitologiia. 1977 Jun;19(6):692-5.
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[Nycthemeral variations of mitotic activity in the adrenal cortex of the rat].
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8
[Effect of thyroxine on the diurnal rhythm of the mitotic activity and parameters of the life cycle of cells of the liver and esophagus].[甲状腺素对肝脏和食管细胞有丝分裂活性昼夜节律及细胞生命周期参数的影响]
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9
[Interaction of the circadian rhythms of the functional activity of the hypophyseal-adrenal system and of the mitotic activity in the esophageal epithelium of rats with experimental hypo- and hypercorticism].
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[Effect of chronic pyrogenal stress on the mitotic regime and quantity of DNA-synthesizing cells in the epithelium of the cornea and tongue of white rats].[慢性热原性应激对白鼠角膜和舌上皮细胞有丝分裂状态及DNA合成细胞数量的影响]
Biull Eksp Biol Med. 1978 Aug;86(8):248-50.