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原发性甲状旁腺功能亢进症:保守性手术的情况

Primary hyperparathyroidism: the case for conservative surgery.

作者信息

Kelly T R

出版信息

Am Surg. 1980 Apr;46(4):230-2.

PMID:7386986
Abstract

Analysis of a series of 205 surgically treated cases of primary hyperparathyroidism was carried out to assess the long-term results of the conservative approach of selectively removing the adenoma only. If primary hyperparathyroidism is due to multiple gland involvement in one-third to one-half of patients, an appreciable number of patients with recurrent disease should have been encountered during this study of the results of conservative no instances of permanent tetany, supports the conservative approach to the treatment when only a single enlarged gland is encountered. Subtotal parathyroidectomy should be reserved for those few cases in which multiple enlarged glands are found, especially in association with multiple endocrine neoplasm, familial hyperparathyroidism, and secondary hyperparathyroidism.

摘要

对205例接受手术治疗的原发性甲状旁腺功能亢进症病例进行了分析,以评估仅选择性切除腺瘤的保守治疗方法的长期效果。如果原发性甲状旁腺功能亢进症在三分之一至二分之一的患者中是由于多腺体受累引起的,那么在这项保守治疗结果的研究中应该会遇到相当数量的复发疾病患者。没有永久性手足搐搦的病例,支持在仅发现一个增大腺体时采用保守治疗方法。甲状旁腺次全切除术应保留给那些发现多个增大腺体的少数病例,特别是与多发性内分泌肿瘤、家族性甲状旁腺功能亢进症和继发性甲状旁腺功能亢进症相关的病例。

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