儿童佐林格-埃利森综合征：西咪替丁的药物治疗

Drake D P, Maciver A G, Atwell J D

Arch Dis Child. 1980 Mar;55(3):226-8. doi: 10.1136/adc.55.3.226.

A 12-year-old boy presented with intestinal obstruction associated with duodenal and oesophageal ulceration. At laparotomy he was found to have an islet cell tumour in the right lobe of the liver. Gastroenterostomy was performed. Raised levels of serum gastrin were detected. Treatment with cimetidine has produced satisfactory control of his symptoms for 16 months, and is an acceptable alternative to total gastrectomy in childhood.

一名12岁男孩因十二指肠和食管溃疡伴肠梗阻就诊。剖腹探查时发现他的肝脏右叶有一个胰岛细胞瘤。进行了胃肠吻合术。检测到血清胃泌素水平升高。西咪替丁治疗使他的症状得到了16个月的满意控制，是儿童期全胃切除术的一种可接受的替代方法。