Shagan B P, Friedman S A
Arch Intern Med. 1980 Jun;140(6):832-3.
We describe a patient with panhypopituitarism whose only clinical symptoms were related to Raynaud's phenomenon. Previously described patients with Raynaud's phenomenon due to hypothyroidism had Hashimoto's thyroiditis, an autoimmune disease associated with multisystem autoimmune disorders. The occurrence of Raynaud's phenomenon in hypothyroidism without thyroiditis and its prompt disappearance with thyroid replacement therapy demonstrate that decreased thyroid function per se is a cause of this vasospastic syndrome. Raynaud's phenomenon may be an early clue to the diagnosis of hypothyroidism.
我们描述了一名全垂体功能减退患者，其唯一的临床症状与雷诺现象有关。先前描述的因甲状腺功能减退导致雷诺现象的患者患有桥本甲状腺炎，这是一种与多系统自身免疫性疾病相关的自身免疫性疾病。在无甲状腺炎的甲状腺功能减退症中出现雷诺现象，以及甲状腺替代治疗后其迅速消失，表明甲状腺功能本身下降是这种血管痉挛综合征的一个原因。雷诺现象可能是甲状腺功能减退症诊断的早期线索。
