Alvarez F E, Greco R S
Arch Surg. 1980 Jun;115(6):772-5. doi: 10.1001/archsurg.1980.01380060070021.
Overwhelming postsplenectomy infection is a well-defined clinical entity resulting from the inability of the splenectomized host to combat infections with encapsulated bacteria. Because of this lethal complication, a number of alternatives to splenectomy have been studied, including autotransplantation of the removed spleen or partial splenectomy. The ability of the splenic tissue to regenerate depends on the type of procedure selected. In this study, the regenerating capacity of the splenic tissue is studied in 99 Sprague-Dawley rats. These animals were subjected to surgical autotransplantation and partial splenectomy. Our results demonstrated the superiority of partial splenectomy over autotransplantation in terms of regeneration of the splenic mass.
脾切除术后暴发性感染是一种明确的临床病症，是由于脾切除后的宿主无法抵抗包膜细菌感染所致。由于这种致命的并发症，人们研究了多种脾切除术的替代方法，包括切除脾脏的自体移植或部分脾切除术。脾组织的再生能力取决于所选的手术方式。在本研究中，对99只Sprague-Dawley大鼠的脾组织再生能力进行了研究。这些动物接受了手术自体移植和部分脾切除术。我们的结果表明，在脾质量再生方面，部分脾切除术优于自体移植。
