用分离的肝细胞研究溴苯诱导细胞毒性的机制。 - Suppr

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The mechanism of bromobenzene-induced cytotoxicity studied with isolated hepatocytes.

作者信息

Thor H, Orrenius S

出版信息

Arch Toxicol. 1980 Mar;44(1-3):31-43. doi: 10.1007/BF00303181.

DOI:10.1007/BF00303181

PMID:7387401

Abstract

摘要

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ENZYME-STRUCTURE RELATIONSHIPS IN THE ENDOPLASMIC RETICULUM OF RAT LIVER : A Morphological and Biochemical Study.内质网中大鼠肝脏的酶结构关系：形态学和生物化学研究。

J Cell Biol. 1962 Dec 1;15(3):541-62. doi: 10.1083/jcb.15.3.541.

Enzyme-catalysed conjugations of glutathione with unsaturated compounds.谷胱甘肽与不饱和化合物的酶催化共轭反应。

Biochem J. 1967 Jul;104(1):95-102. doi: 10.1042/bj1040095.

Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite.溴苯诱导的肝坏死。谷胱甘肽的保护作用及3,4-溴苯氧化物作为肝毒性代谢物的证据。

Pharmacology. 1974;11(3):151-69. doi: 10.1159/000136485.

A purified plasma membrane fraction isolated from rat liver under isotonic conditions.

Biochim Biophys Acta. 1967 Sep 9;135(4):573-9. doi: 10.1016/0005-2736(67)90089-2.

A study of drug metabolism linked to cytochrome P-450 in isolated rat-liver cells.

Eur J Biochem. 1974 Jul 15;46(2):351-60. doi: 10.1111/j.1432-1033.1974.tb03627.x.

Decrease in glutathione levels of kidney and liver after injection of methionine sulfoximine into rats.向大鼠注射蛋氨酸亚砜亚胺后肾脏和肝脏中谷胱甘肽水平的降低。

Biochem Biophys Res Commun. 1975 Feb 3;62(3):651-7. doi: 10.1016/0006-291x(75)90448-9.

Oxidative and conjugative metabolism of p-nitroanisole and p-nitrophenol in isolated rat liver cells.对硝基苯甲醚和对硝基苯酚在离体大鼠肝细胞中的氧化和结合代谢

Acta Pharmacol Toxicol (Copenh). 1976 Jul;39(1):17-32. doi: 10.1111/j.1600-0773.1976.tb03151.x.

The role of methionine in glutathione biosynthesis by isolated hepatocytes.蛋氨酸在分离的肝细胞谷胱甘肽生物合成中的作用。

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Metabolism of benzo(a)pyrene with isolated hepatocytes and the formation and degradation of DNA-binding derivatives.

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Paracetamol metabolism and toxicity in isolated hepatocytes from rat and mouse.对乙酰氨基酚在大鼠和小鼠离体肝细胞中的代谢与毒性

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