谷胱甘肽与不饱和化合物的酶催化共轭反应。
Enzyme-catalysed conjugations of glutathione with unsaturated compounds.
作者信息
Boyland E, Chasseaud L F
出版信息
Biochem J. 1967 Jul;104(1):95-102. doi: 10.1042/bj1040095.
Abstract
- Rat-liver supernatant catalyses the reaction of diethyl maleate with glutathione. 2. Evidence is presented that the enzyme involved is different from the known glutathione-conjugating enzymes, glutathione S-alkyltransferase, S-aryltransferase and S-epoxidetransferase. 3. Rat-liver supernatant catalyses the reaction of a number of other alphabeta-unsaturated compounds, including aldehydes, ketones, lactones, nitriles and nitro compounds, with glutathione: separate enzymes may be responsible for these reactions.
摘要
- 大鼠肝脏上清液催化马来酸二乙酯与谷胱甘肽的反应。2. 有证据表明，所涉及的酶不同于已知的谷胱甘肽结合酶、谷胱甘肽S - 烷基转移酶、S - 芳基转移酶和S - 环氧化合物转移酶。3. 大鼠肝脏上清液催化许多其他αβ - 不饱和化合物，包括醛、酮、内酯、腈和硝基化合物与谷胱甘肽的反应：可能有不同的酶负责这些反应。
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