• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Enzyme-catalysed conjugations of glutathione with unsaturated compounds.谷胱甘肽与不饱和化合物的酶催化共轭反应。
Biochem J. 1967 Jul;104(1):95-102. doi: 10.1042/bj1040095.
2
Enzymes catalysing conjugations of glutathione with alpha-beta-unsaturated carbonyl compounds.催化谷胱甘肽与α-β-不饱和羰基化合物结合的酶。
Biochem J. 1968 Oct;109(4):651-61. doi: 10.1042/bj1090651.
3
Studies on glutathione S-alkyltransferase of the rat.大鼠谷胱甘肽S-烷基转移酶的研究。
Biochem J. 1966 Jan;98(1):44-56. doi: 10.1042/bj0980044.
4
The effect of some carbonyl compounds on rat liver glutathione levels.某些羰基化合物对大鼠肝脏谷胱甘肽水平的影响。
Biochem Pharmacol. 1970 Apr;19(4):1526-8. doi: 10.1016/0006-2952(70)90075-4.
5
Glutathione S-aralkyltransferase.谷胱甘肽S-芳烷基转移酶
Biochem J. 1969 Dec;115(5):985-91. doi: 10.1042/bj1150985.
6
Conjugations with glutathione. Distribution of glutathione S-aryltransferase in vertebrate species.与谷胱甘肽的结合。谷胱甘肽S-芳基转移酶在脊椎动物物种中的分布。
Biochem J. 1964 Mar;90(3):603-6. doi: 10.1042/bj0900603.
7
Phosphoric acid triester glutathione alkyltransferase. A mechanism for the detoxification of dimethyl phosphate triesters.磷酸三酯谷胱甘肽烷基转移酶。磷酸二甲酯三酯的解毒机制。
Biochem J. 1972 Mar;127(1):285-93. doi: 10.1042/bj1270285.
8
The mechanism of the reaction between glutathione and 1-menaphthyl sulphate catalysed by a glutathione S-transferase from rat liver.大鼠肝脏谷胱甘肽S-转移酶催化谷胱甘肽与1-萘基硫酸盐反应的机制。
Biochem J. 1973 Dec;135(4):797-804. doi: 10.1042/bj1350797.
9
Intracellular Metabolism of α,β-Unsaturated Carbonyl Compounds, Acrolein, Crotonaldehyde and Methyl Vinyl Ketone, Active Toxicants in Cigarette Smoke: Participation of Glutathione Conjugation Ability and Aldehyde-Ketone Sensitive Reductase Activity.α,β-不饱和羰基化合物、丙烯醛、巴豆醛和甲基乙烯基酮在细胞内的代谢，香烟烟雾中的活性毒物：谷胱甘肽结合能力和醛酮敏感还原酶活性的参与
Chem Pharm Bull (Tokyo). 2016;64(6):585-93. doi: 10.1248/cpb.c15-00986.
10
CONJUGATIONS WITH GLUTATHIONE. THE ENZYMIC CONJUGATION OF SOME CHLOROCYCLOHEXENES.与谷胱甘肽的结合。某些氯代环己烯的酶促结合
Biochem J. 1965 Apr;95(1):156-60. doi: 10.1042/bj0950156.

引用本文的文献

1
Differential Effects of Itaconate and its Esters on the Glutathione and Glucose Metabolism of Cultured Primary Rat Astrocytes.异丁烯酸及其酯类对原代培养大鼠星形胶质细胞谷胱甘肽和葡萄糖代谢的差异影响。
Neurochem Res. 2024 Nov 20;50(1):24. doi: 10.1007/s11064-024-04263-0.
2
NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation.NINJ1 通过 xCT 转运体相互作用和 CoA 调节来调控铁死亡。
Cell Death Dis. 2024 Oct 18;15(10):755. doi: 10.1038/s41419-024-07135-1.
3
Lipid-derived electrophiles inhibit the function of membrane channels during ferroptosis.脂质衍生的亲电物在铁死亡期间抑制膜通道的功能。
Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2317616121. doi: 10.1073/pnas.2317616121. Epub 2024 May 14.
4
NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation.NINJ1通过xCT反向转运体相互作用和辅酶A调节来调控铁死亡。
bioRxiv. 2024 Feb 27:2024.02.22.581432. doi: 10.1101/2024.02.22.581432.
5
Glutathione and Glutaredoxin-Key Players in Cellular Redox Homeostasis and Signaling.谷胱甘肽和谷氧还蛋白——细胞氧化还原稳态与信号传导中的关键因子
Antioxidants (Basel). 2023 Aug 3;12(8):1553. doi: 10.3390/antiox12081553.
6
A tau class GST, OsGSTU5, interacts with VirE2 and modulates the Agrobacterium-mediated transformation in rice.一种tau类谷胱甘肽S-转移酶（OsGSTU5）与VirE2相互作用，并调节农杆菌介导的水稻转化。
Plant Cell Rep. 2022 Apr;41(4):873-891. doi: 10.1007/s00299-021-02824-z. Epub 2022 Jan 24.
7
Redox Regulation by Protein S-Glutathionylation: From Molecular Mechanisms to Implications in Health and Disease.蛋白质 S-谷胱甘肽化的氧化还原调控：从分子机制到对健康和疾病的影响。
Int J Mol Sci. 2020 Oct 30;21(21):8113. doi: 10.3390/ijms21218113.
8
Exploring the Use of Dimethyl Fumarate as Microglia Modulator for Neurodegenerative Diseases Treatment.探索富马酸二甲酯作为小胶质细胞调节剂用于治疗神经退行性疾病
Antioxidants (Basel). 2020 Aug 3;9(8):700. doi: 10.3390/antiox9080700.
9
Dysregulation of the glutaredoxin/glutathionylation redox axis in lung diseases.肺疾病中谷氧还蛋白/谷胱甘肽化氧化还原轴的失调。
Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C304-C327. doi: 10.1152/ajpcell.00410.2019. Epub 2019 Nov 6.
10
Boosting GSH Using the Co-Drug Approach: I-152, a Conjugate of -acetyl-cysteine and β-mercaptoethylamine.使用联合用药方法增强 GSH：I-152，半胱氨酸和β-巯基乙胺的缀合物。
Nutrients. 2019 Jun 7;11(6):1291. doi: 10.3390/nu11061291.

本文引用的文献

1
The toxicity of methyl and ethyl acrylate.甲基丙烯酸甲酯和丙烯酸乙酯的毒性。
J Ind Hyg Toxicol. 1949 Nov;31(6):317-26.
2
AN ENZYME CATALYSING THE CONJUGATION OF EPOXIDES WITH GLUTATHIONE.一种催化环氧化物与谷胱甘肽结合的酶。
Biochem J. 1965 Jan;94(1):190-7. doi: 10.1042/bj0940190.
3
CARCINOGENIC LACTONES AND RELATED SUBSTANCES.致癌内酯及相关物质。
Br Med Bull. 1964 May;20:96-101. doi: 10.1093/oxfordjournals.bmb.a070324.
4
An enzyme from rat liver catalysing conjugations with glutathione. 2. Replacement of nitro groups.一种来自大鼠肝脏的可催化与谷胱甘肽结合反应的酶。2. 硝基的取代。
Biochem J. 1963 Apr;87(1):4-9. doi: 10.1042/bj0870004.
5
Acidic peptides of the lens. 8. S-(alpha beta-dicarboxyethyl) glutathione.晶状体的酸性肽。8. S-（αβ-二羧乙基）谷胱甘肽。
Biochem J. 1963 Feb;86(2):226-31. doi: 10.1042/bj0860226.
6
A liver enzyme that conjugates sulfobromophthalein sodium with glutathione.一种能使磺溴酞钠与谷胱甘肽结合的肝脏酶。
J Clin Invest. 1961 Jun;40(6):981-8. doi: 10.1172/JCI104337.
7
[Effect of kidney homogenates on the reaction of glutathione with maleic acid].[肾脏匀浆对谷胱甘肽与马来酸反应的影响]
Acta Biochim Pol. 1961;8:89-103.
8
The formation of mercapturic acids. 2. The possible role of glutathionase.硫醇尿酸的形成。2. 谷胱甘肽酶的可能作用。
Biochem J. 1959 Apr;71(4):690-6. doi: 10.1042/bj0710690.
9
The formation of mercapturic acids. 1. Formation of mercapturic acid and the levels of glutathione in tissues.巯基尿酸的形成。1. 巯基尿酸的形成及组织中谷胱甘肽的水平。
Biochem J. 1959 Apr;71(4):680-90. doi: 10.1042/bj0710680.
10
Tissue sulfhydryl groups.组织巯基
Arch Biochem Biophys. 1959 May;82(1):70-7. doi: 10.1016/0003-9861(59)90090-6.

谷胱甘肽与不饱和化合物的酶催化共轭反应。

Enzyme-catalysed conjugations of glutathione with unsaturated compounds.

作者信息

Boyland E, Chasseaud L F

出版信息

Biochem J. 1967 Jul;104(1):95-102. doi: 10.1042/bj1040095.

DOI:10.1042/bj1040095
PMID:6035529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1270549/
Abstract
  1. Rat-liver supernatant catalyses the reaction of diethyl maleate with glutathione. 2. Evidence is presented that the enzyme involved is different from the known glutathione-conjugating enzymes, glutathione S-alkyltransferase, S-aryltransferase and S-epoxidetransferase. 3. Rat-liver supernatant catalyses the reaction of a number of other alphabeta-unsaturated compounds, including aldehydes, ketones, lactones, nitriles and nitro compounds, with glutathione: separate enzymes may be responsible for these reactions.
摘要
  1. 大鼠肝脏上清液催化马来酸二乙酯与谷胱甘肽的反应。2. 有证据表明，所涉及的酶不同于已知的谷胱甘肽结合酶、谷胱甘肽S - 烷基转移酶、S - 芳基转移酶和S - 环氧化合物转移酶。3. 大鼠肝脏上清液催化许多其他αβ - 不饱和化合物，包括醛、酮、内酯、腈和硝基化合物与谷胱甘肽的反应：可能有不同的酶负责这些反应。