利用显微分光荧光测定法对肝细胞进行毒理学研究。
Toxicological studies of liver cells by microspectrofluorometry.
作者信息
Stier A, Nolte K H, Schlenker A, Schumann W, Zuretti F M
出版信息
Arch Toxicol. 1980 Mar;44(1-3):45-54. doi: 10.1007/BF00303182.
PMID:7387402
Abstract
The kinetics of xenobiotic biotransformation was measured in single, isolated, perifused liver cells with microspectrofluorometry using highly sensitive photodetection systems. A program of further applications to biochemical toxicological problems is presented.
摘要
利用高灵敏度光检测系统，通过显微分光荧光测定法在单个、分离的灌注肝细胞中测量了外源化合物生物转化的动力学。本文还介绍了在生化毒理学问题上的进一步应用计划。
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