Vikhruk T I
Arkh Anat Gistol Embriol. 1980 Feb;78(2):25-9.
In histological preparations of the inguinal lymph nodes of white rats subjected to repeated physical loading percentage correlation of structural component areas in the nodes was estimated. A. A. Glagolev's morphometric grid in S. B. Stefanov's modification was used. Dynamic loading for 5 months was stated to produce a number of changes in the lymph nodes under investigation depending on duration of the experiment and on the level of the animals' adaptation to the loading. Most pronounced changes were noted in the medullar substance, with predominance of follicles having light centers, while its area increased sharply at the expense of diffusively outgrowing lymphoid tissue that did not occur under normal conditions. Certain changes were detected in stroma of the nodes--their capsule became more powerful, while trabecules, on the contrary, occupied less area than in the control. The areas in the node occupied by vessels grew larger. Normally trained rats demonstrated maximal changes in 3 months, and then the structure of the node did not differ from that in the control. In overtrained animals, by the 5th month, many indices differed greatly from those in the control.