Morris H H, McCormick W F, Reinarz J A
Arch Neurol. 1980 Jul;37(7):462-3. doi: 10.1001/archneur.1980.00500560092019.
The neuroleptic malignant syndrome is an uncommon, severe illness that consists of fever, muscular rigidity, and stupor. Various neuroleptics have been associated with the disease. A detailed neurological, medical, and neuropathological evaluation of this case was performed. Presumably, the syndrome is secondary to biochemical dysfunction of the basal ganglia and possible of the hypothalmus.
抗精神病药物恶性综合征是一种罕见的严重疾病,表现为发热、肌肉强直和木僵。多种抗精神病药物都与该疾病有关。对该病例进行了详细的神经学、医学和神经病理学评估。据推测,该综合征继发于基底神经节以及可能的下丘脑的生化功能障碍。