Squires E J, Feltham L A
Biochem J. 1980 Mar 1;185(3):761-6. doi: 10.1042/bj1850761.
A ninhydrin-positive compound was isolated from the plasma of the winter flounder (Pseudopleuronectes americanus) and identified as the isodipeptide N-epsilon-(gamma-glutamyl)-lysine. Wide seasonal variations in plasma concentration of this compound are found in the male flounder, whereas it is present only in trace amounts in the plasma of the female flounder throughout the year. In the male flounder the plasma concentration of N-epsilon-(gamma-glutamyl)-lysine rises from January to a peak in May and June. It is during these latter months that the flounder spawn. After spawning, the plasma concentration of the isodipeptide decreases to low basal values in October. These changes in plasma concentration of N-epsilon-(gamma-glutamyl)-lysine may be related to changes in testes weight, spermatogenesis and spawning activity of the winter flounder.
从美洲拟庸鲽的血浆中分离出一种茚三酮阳性化合物,鉴定为异二肽N-ε-(γ-谷氨酰基)-赖氨酸。雄性拟庸鲽血浆中该化合物的浓度存在很大的季节性变化,而雌性拟庸鲽血浆中全年仅存在微量该化合物。在雄性拟庸鲽中,N-ε-(γ-谷氨酰基)-赖氨酸的血浆浓度从1月开始上升,在5月和6月达到峰值。正是在这几个月里,拟庸鲽产卵。产卵后,异二肽的血浆浓度在10月降至低基础值。N-ε-(γ-谷氨酰基)-赖氨酸血浆浓度的这些变化可能与美洲拟庸鲽的睾丸重量、精子发生和产卵活动的变化有关。