Asmussen I
Br J Obstet Gynaecol. 1980 Mar;87(3):239-45. doi: 10.1111/j.1471-0528.1980.tb04527.x.
The ultrastructure of placental villi from 10 heavy smokers (10 greater than or equal to cigarettes per day) was compared with that of 16 nonsmokers (never smoked). Thickening of the basement membrane and increase in collagen content of the villous stroma was found. The fetal capillaries were fewer in number and with decreased lumen either due to oedema or contraction of the endothelial cells. All cells, both in the fetal capillaries as well as syncytiotrophoblast and cytotrophoblast contained large amounts of filaments and fibrillae possibly capable of cell contraction. Thus a result of these findings might be a decreased placental flow in smokers.
将10名重度吸烟者（每天吸烟10支及以上）的胎盘绒毛超微结构与16名不吸烟者（从不吸烟）的进行比较。发现基底膜增厚，绒毛间质胶原含量增加。胎儿毛细血管数量减少，管腔因水肿或内皮细胞收缩而减小。胎儿毛细血管、合体滋养层细胞和细胞滋养层细胞内的所有细胞均含有大量可能具有细胞收缩能力的细丝和原纤维。因此，这些发现的一个结果可能是吸烟者胎盘血流量减少。
