Berkinblit M B, Deliagina T G, Orlovsky G N, Feldman A G
Brain Res. 1980 Jul 14;193(2):427-38. doi: 10.1016/0006-8993(80)90175-4.
(1) Intracellular recording of motoneurons of different hindlimb muscles: tibialis anterior (TA), gastrocnemius and soleus (GS), vastus crureus (Vast), posterior biceps and semitendinosus (PBSt), was carried out during the fictitious scratch reflex in decerebrate cats. (2) During the postural stage of the reflex, a depolarizaiton (3.8 mV on average) was observed in TA motoneurons accompanied by tonic discharge. No change of the membrane potential (MP) and no discharge were observed during this stage in GS, Vast and PBSt motoneurons. (3) In the rhythmical stage of the reflex, the MP of TA motoneurons changed only slightly during the 'long' (L) phase of the scratch cycle and remained at approximately the same level as during the postural stage. In this phase, motoneurons discharged at frequencies of 20-100 pps. In the 'short' (S) phase of the scratch cycle a strong repolarization occurred, the MP reached the same level as observed during resting conditons (MP0), and the discharge discontinued. (4) GS motoneurons were gradually depolarized during the second half of the L-phase. The depolarization reached its maximum (5.5 mV on average in relation to the MP0) on average in relation to the MP0) in the S-phase, and several action potentials were generated with intervals of 5-10 msec. Then, at the beginning of the L-phase, the motoneurons were repolarized and the MP reached the level of the MP0. The behavior of Vast motoneurons was essentially similar to that of GS motoneurons. (5) The PBSt motoneurons usually had two peaks of depolarization per cycle--in the S-phase and at the beginning of the L-phase. The maximal depolarization was 3.5 mV (on average). The motoneurons generated action potentials at one or both peaks of depolarization. (6) The possible organization of the central influences upon motoneurons of different muscles during scratching is discussed.
(1) 在去大脑猫的假想搔抓反射过程中，对不同后肢肌肉的运动神经元进行了细胞内记录，这些肌肉包括胫骨前肌（TA）、腓肠肌和比目鱼肌（GS）、股直肌（Vast）、股二头肌后群和半腱肌（PBSt）。(2) 在反射的姿势阶段，观察到TA运动神经元出现去极化（平均3.8 mV）并伴有紧张性放电。在这个阶段，GS、Vast和PBSt运动神经元的膜电位（MP）没有变化，也没有放电。(3) 在反射的节律阶段，TA运动神经元的MP在搔抓周期的“长”（L）相仅略有变化，并且保持在与姿势阶段大致相同的水平。在这个阶段，运动神经元以20 - 100次/秒的频率放电。在搔抓周期的“短”（S）相发生强烈复极化，MP达到与静息状态（MP0）观察到的相同水平，并且放电停止。(4) GS运动神经元在L相后半期逐渐去极化。去极化在S相达到最大值（相对于MP0平均为5.5 mV），并以5 - 10毫秒的间隔产生几个动作电位。然后，在L相开始时，运动神经元复极化，MP达到MP0水平。Vast运动神经元的行为与GS运动神经元基本相似。(5) PBSt运动神经元通常每个周期有两个去极化峰值——在S相和L相开始时。最大去极化平均为3.5 mV。运动神经元在一个或两个去极化峰值处产生动作电位。(6) 讨论了搔抓过程中对不同肌肉运动神经元的中枢影响的可能组织方式。
