Rogers J S, Shah S
Cancer. 1980 Jul 1;46(1):212-4. doi: 10.1002/1097-0142(19800701)46:1<212::aid-cncr2820460135>3.0.co;2-i.
A case of plasma cell leukemia complicated by spontaneous rupture of the spleen is presented. Plasma cell leukemia occurs in less than 2% of patients with myeloma and is associated with an increased incidence of splenomegaly due to infiltration by malignant plasmacytes. Sontaneous splenic rupture is known to occur in patients with acute and chronic leukemia, but has been reported only once previously in a patient with plasma cell leukemia. Etiologic factors and the need for prompt diagnosis and management are discussed.
本文报告1例浆细胞白血病合并脾自发性破裂的病例。浆细胞白血病在骨髓瘤患者中的发生率不到2%,并且由于恶性浆细胞浸润导致脾肿大的发生率增加。已知急性和慢性白血病患者会发生脾自发性破裂,但此前仅有1例浆细胞白血病患者有相关报道。本文讨论了病因以及及时诊断和处理的必要性。