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Benzene is metabolized and covalently bound in bone marrow in situ.

作者信息

Irons R D, Dent J G, Baker T S, Rickert D E

出版信息

Chem Biol Interact. 1980 May;30(2):241-5. doi: 10.1016/0009-2797(80)90130-1.

DOI:10.1016/0009-2797(80)90130-1
PMID:7389002
Abstract
摘要

相似文献

1
Benzene is metabolized and covalently bound in bone marrow in situ.苯在骨髓原位发生代谢并共价结合。
Chem Biol Interact. 1980 May;30(2):241-5. doi: 10.1016/0009-2797(80)90130-1.
2
Benzene increases protein-bound 3-nitrotyrosine in bone marrow of B6C3F1 mice.
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Analytical approaches to the study of the disposition of myelotoxic agents.骨髓毒性药物处置研究的分析方法。
Environ Health Perspect. 1981 Jun;39:5-10. doi: 10.1289/ehp.81395.
4
Methyl-substitution of benzene and toluene in preparations of human bone marrow.人体骨髓制剂中苯和甲苯的甲基取代
Life Sci. 1991;48(8):843-50. doi: 10.1016/0024-3205(91)90100-p.
5
The use of protein adducts to investigate the disposition of reactive metabolites of benzene.利用蛋白质加合物研究苯的活性代谢物的处置情况。
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6
Bone marrow DNA adducts and bone marrow cellularity following treatment with benzene metabolites in vivo.体内用苯代谢物治疗后的骨髓DNA加合物和骨髓细胞密度
Adv Exp Med Biol. 1991;283:745-8. doi: 10.1007/978-1-4684-5877-0_98.
7
Detection of nitrated benzene metabolites in bone marrow of B6C3F1 mice treated with benzene.
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8
Benzene disposition in the rat after exposure by inhalation.大鼠吸入暴露后苯的处置情况。
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9
Toxicological and biochemical effects of repeated administration of benzene in mice.苯重复给药对小鼠的毒理学和生化效应。
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10
Binding of labeled benzene metabolites to mouse liver and bone marrow.标记的苯代谢物与小鼠肝脏和骨髓的结合。
Res Commun Chem Pathol Pharmacol. 1978 Apr;20(1):191-4.

引用本文的文献

1
Occupational Benzene Exposure and Cancer Risk among Chinese Men: A Report from the Shanghai Men's Health Study.职业苯暴露与中国男性癌症风险:来自上海男性健康研究的报告。
Cancer Epidemiol Biomarkers Prev. 2024 Nov 1;33(11):1465-1474. doi: 10.1158/1055-9965.EPI-24-0325.
2
The use of biomonitoring data in exposure and human health risk assessment: benzene case study.生物监测数据在暴露和人体健康风险评估中的应用:以苯为例。
Crit Rev Toxicol. 2013 Feb;43(2):119-53. doi: 10.3109/10408444.2012.756455.
3
Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers.
苯暴露工人造血祖细胞中检测到与白血病相关的染色体缺失。
Leukemia. 2012 Dec;26(12):2494-8. doi: 10.1038/leu.2012.143. Epub 2012 May 30.
4
Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment.当前对人类苯致白血病机制的认识:对风险评估的启示。
Carcinogenesis. 2012 Feb;33(2):240-52. doi: 10.1093/carcin/bgr297. Epub 2011 Dec 12.
5
An overview of benzene metabolism.苯代谢概述。
Environ Health Perspect. 1996 Dec;104 Suppl 6(Suppl 6):1165-71. doi: 10.1289/ehp.961041165.
6
Chromosome alterations in peripheral lymphocytes as indices of lifestyle and genotoxicity.外周淋巴细胞中的染色体改变作为生活方式和遗传毒性的指标。
Int Arch Occup Environ Health. 1993;65(1 Suppl):S37-41. doi: 10.1007/BF00381305.
7
The toxicology of benzene.苯的毒理学
Environ Health Perspect. 1993 Apr;100:293-306. doi: 10.1289/ehp.93100293.
8
Benzene toxicity and risk assessment, 1972-1992: implications for future regulation.苯毒性与风险评估,1972 - 1992:对未来监管的启示
Environ Health Perspect. 1993 Dec;101 Suppl 6(Suppl 6):177-200. doi: 10.1289/ehp.93101s6177.
9
Analytical approaches to the study of the disposition of myelotoxic agents.骨髓毒性药物处置研究的分析方法。
Environ Health Perspect. 1981 Jun;39:5-10. doi: 10.1289/ehp.81395.
10
Effects of pretreatment of male NMRI mice with enzyme inducers or inhibitors on clastogenicity of toluene.用酶诱导剂或抑制剂对雄性NMRI小鼠进行预处理对甲苯致染色体断裂性的影响。
Arch Toxicol. 1987 Aug;60(6):460-3. doi: 10.1007/BF00302390.