Dozois R R, Madson T H, Dousa T P
Dig Dis Sci. 1980 Apr;25(4):273-8. doi: 10.1007/BF01308517.
The effects of prostaglandin precursors, namely an analog of prostaglandin endoperoxide PGH2 [(15S)-hydroxy-9 alpha,11 alpha-(epoxymethano)prosta-5,13-dienoic acid] and arachidonic acid, were assessed on gastric adenylate cyclase activity from cell-free preparations of guinea pig fundic mucosa. The two precursors were tested against basal adenylate cyclase activity and that simulated by histamine (10(-4) M), by PGE2(10(-4) M), by 5
评估了前列腺素前体，即前列腺素内过氧化物PGH2的类似物[（15S）-羟基-9α，11α-（环氧亚甲基）前列腺-5,13-二烯酸]和花生四烯酸对豚鼠胃底黏膜无细胞制剂中胃腺苷酸环化酶活性的影响。将这两种前体与基础腺苷酸环化酶活性以及由组胺（10⁻⁴ M）、PGE2（10⁻⁴ M）、5模拟的活性进行了比较。
