Goulon M, Raphael J C, Gajdos P, Barois A, Babinet P, Margent P
Intensive Care Med. 1978 Nov;4(4):173-9. doi: 10.1007/BF01902544.
Extracorporeal circulation with a membrane oxygenator (ECMO) was used in 11 patients with acute respiratory insufficiency who did not respond to conventional treatment. By pass was veno-arterial in every case, seven times with femoral artery return, three times with axillary artery return, and once with both femoral and axillary return. Five patients died on ECMO. Six patients were taken off ECMO and two of them are long-term survivors. In nine cases ECMO allowed short-term control of respiratory failure. The respective roles of oxygen supply from ECMO and the haemodynamic changes incurred by its use are discussed. Although use of ECMO for long periods seems less hazardous now, present results are restricted by the lack of therapy for the underlying pulmonary lesions.
11例对常规治疗无反应的急性呼吸功能不全患者使用了带有膜式氧合器的体外循环（ECMO）。所有病例均采用静脉-动脉旁路，7次通过股动脉回流，3次通过腋动脉回流，1次同时采用股动脉和腋动脉回流。5例患者在ECMO治疗期间死亡。6例患者撤掉了ECMO，其中2例为长期存活者。9例患者通过ECMO实现了呼吸衰竭的短期控制。文中讨论了ECMO供氧的各自作用及其使用引起的血流动力学变化。尽管现在长时间使用ECMO似乎危害较小，但目前的结果受到潜在肺部病变缺乏治疗方法的限制。
