Plotnik G D, Fisher M L, Carliner N H, Becker L C
JAMA. 1980 Aug 8;244(6):574-6. doi: 10.1001/jama.244.6.574.
Among patients with unstable angina pectoris, those with crescendo angina seem to be at high risk for death and myocardial infarction. We reviewed the clinical, arteriographic, and hemodynamic findings in 218 consecutive catheterized patients with unstable angina. Unstable angina was defined as ischemic cardiac pain at rest associated with transient ECG changes but no evidence for acute myocardial infarction. Patients were divided into two groups according to the duration of symptoms: 134 patients with crescendo angina (new, or increasing, rest pain with previous ischemic symptoms present for more than three months) and 84 with recent onset angina (symptoms present for less than three months). Compared with patients with recent onset symptoms, patients with crescendo angina had more extensive coronary disease and lower ejection fractions, which may explain their poor prognosis.
在不稳定型心绞痛患者中，进行性加重性心绞痛患者似乎死亡和心肌梗死风险较高。我们回顾了218例连续接受心导管检查的不稳定型心绞痛患者的临床、血管造影和血流动力学检查结果。不稳定型心绞痛定义为静息时缺血性心前区疼痛伴短暂心电图改变，但无急性心肌梗死证据。根据症状持续时间将患者分为两组：134例进行性加重性心绞痛患者（新发或加重的静息性疼痛，既往有缺血症状超过3个月）和84例近期发作性心绞痛患者（症状出现少于3个月）。与近期发作症状患者相比，进行性加重性心绞痛患者的冠状动脉病变更广泛，射血分数更低，这可能解释了他们预后较差的原因。
