Pullicino P, Kendall B E
Neuroradiology. 1980;19(5):235-9. doi: 10.1007/BF00347801.
The contribution of post-enhancement CT scans to the diagnosis of acute cerebral infarction was studied in a consecutive series of infarcts. The timing, density and pattern of enhancement were also analysed for any possible prognostic information, and the incidence of factors of known prognostic significance was estimated on plain and contrast enhanced scans. Enhancement patterns of infarcts were variable and in those cases in which the plain CT diagnosis was equivocal the post-enhancement CT was not infrequently ambiguous also, and occasionally misleading. The outcome of infarcts that enhanced was significantly poorer than in those not showing enhancement, although no relationship between the timing, density or pattern of enhancement and prognosis could be shown. Consideration of the distribution of other factors known to adversely affect prognosis in the two groups does not adequately account for the difference between them suggesting that the contrast medium itself could be the cause of the poorer outcome. There are few positive indications for post-contrast scanning of suspected infarcts and the possible adverse effects of contrast medium should be considered prior to administration.
在一系列连续的梗死病例中，研究了增强CT扫描对急性脑梗死诊断的贡献。还分析了强化的时间、密度和模式，以获取任何可能的预后信息，并在平扫和增强扫描中评估已知具有预后意义的因素的发生率。梗死灶的强化模式各不相同，在那些平扫CT诊断不明确的病例中，增强CT也常常模棱两可，偶尔还会产生误导。强化的梗死灶的预后明显比未强化的梗死灶差，尽管强化的时间、密度或模式与预后之间没有相关性。考虑两组中已知对预后有不利影响的其他因素的分布情况，并不能充分解释它们之间的差异，这表明造影剂本身可能是预后较差的原因。对于疑似梗死灶进行增强扫描几乎没有阳性指征，在使用造影剂之前应考虑其可能的不良反应。
