Widgren S
Schweiz Med Wochenschr. 1980 Mar 22;110(12):447-52.
Carcinoma of the pancreas ranks in the 4th place among the causes of death due to tumour in the U.S.A. and the 5th in Geneva. 177 cases of pancreatic carcinoma (necropsies, resections and biopsies) were examined at the Geneva Departement of Pathology between July 1st, 1971 and December 31st, 1978. There was an equal sex distribution among the post-mortem cases while a female predominance (1.5x) was found in the cases obtained by biopsy or surgical resection. The mean age was higher in necropsy cases (69.6 years) than in surgical cases (61.2 years). The most common site was the head of the pancreas (57.5%). Adenocarcinoma was the predominant histologic type (86.5%). The majority of metastases found at necropsy were in the liver (61.3%), regional lymph nodes (51.1%), peritoneum (27.7%) and lungs (26.3%). The most frequent causes of death were lung embolism (24%), bronchopneumonia (16%), tumour or metastases (14.6%) or cachexia (8.8%). Prognosis was always severe, with an average survival time varying between 4 and 10 months depending on the type of surgical treatment (palliative surgery or resection). These results are similar to those of other series in the literature.
在美国，胰腺癌在肿瘤致死病因中位列第四，在日内瓦则位列第五。1971年7月1日至1978年12月31日期间，日内瓦病理科检查了177例胰腺癌病例（尸检、切除及活检）。尸检病例中男女比例均等，而活检或手术切除病例中女性占优势（1.5倍）。尸检病例的平均年龄（69.6岁）高于手术病例（61.2岁）。最常见的部位是胰头（57.5%）。腺癌是主要的组织学类型（86.5%）。尸检时发现的大多数转移部位是肝脏（61.3%）、区域淋巴结（51.1%）、腹膜（27.7%）和肺部（26.3%）。最常见的死亡原因是肺栓塞（24%）、支气管肺炎（16%）、肿瘤或转移（14.6%）或恶病质（8.8%）。预后总是很差，根据手术治疗类型（姑息性手术或切除术），平均生存时间在4至10个月之间。这些结果与文献中其他系列的结果相似。
