Graf J, Schär G, Heinzer I
Schweiz Med Wochenschr. 1980 Apr 19;110(16):590-5.
In a two-center study (Zurich and Berne) covering a 5-month period (September 1979 to January 1980) 665 faeces from patients with diarrhoea and 800 faeces from people without diarrhoea were examined for Campylobacter jejuni. By selective culture Campylobacter jejuni was isolated from 28 faeces of 35 patients with diarrhoea (5,7%) while none of the normal faeces yielded a positive culture. Isolation rates for Salmonellae and Shigellae from the same material (patients with diarrhoea) were 12.6% and 0.9% respectively. Infection with Campylobacter usually causes unspecific enteritis with spontaneous remission after 2--10 days. Occasionally, however, a more severe course initially simulating acute abdominal illness can lead to hospital admission and even to surgical procedures. Symptomatic treatment is suggested for mild cases. In more severe cases, antibiotic therapy is recommended, erythromycin being the drug of choice.
在一项为期5个月(1979年9月至1980年1月)的双中心研究(苏黎世和伯尔尼)中,对665份腹泻患者的粪便和800份无腹泻者的粪便进行了空肠弯曲菌检测。通过选择性培养,从35例腹泻患者的28份粪便中分离出空肠弯曲菌(5.7%),而正常粪便培养均为阴性。同一批材料(腹泻患者)中沙门氏菌和志贺氏菌的分离率分别为12.6%和0.9%。空肠弯曲菌感染通常引起非特异性肠炎,2至10天后可自发缓解。然而,偶尔会出现更严重的病程,最初类似急腹症,可能需要住院甚至进行外科手术。轻症病例建议对症治疗。重症病例推荐使用抗生素治疗,首选药物为红霉素。