Horowitz A J
J Reprod Med. 1978 Oct;21(4):236-40.
The combined use of 40 mg of intraamniotic prostaglandin F2alpha, followed immediately by the insertion of one or more laminaria tents, and of a high-dose oxytocin infusion of 166 milliiunits per minute is a safe, effective, and efficient regime for midtrimester abortion. In 100 consecutive patients between 16 and 20 weeks of gestation, no failures occurred. The mean injection-abortion time was 15.7 hours. Six patients required the reinjection of 20 mg of prostaglandin F2alpha at 24 hours. The placenta was removed with instruments after four hours in 19 patients and done electively in seven patients in less than four hours. Physician-patient contacts were minimized, for all the abortion-initiating techniques were accomplished concomitantly, as opposed to regimes with laminaria pretreatment, or deliberately staggered prostaglandin injections were used. Most of the patients were able to be discharged after one day in the hospital. Thus, the patients' inconvenience and expense were minimized, with no sacrifice in safety.
羊膜腔内联合使用40毫克前列腺素F2α，随后立即插入一个或多个海藻棒，以及以每分钟166毫单位的高剂量输注催产素，是一种用于中期妊娠流产的安全、有效且高效的方案。在100例妊娠16至20周的连续患者中，无一例失败。平均引产至流产时间为15.7小时。6例患者在24小时时需要再次注射20毫克前列腺素F2α。19例患者在4小时后用器械取出胎盘，7例患者在不到4小时内选择性地取出胎盘。由于所有引产起始技术是同时完成的，与海藻棒预处理方案或故意错开前列腺素注射的方案不同，医患接触减至最少。大多数患者在住院一天后即可出院。因此，在不牺牲安全性的情况下，将患者的不便和费用降至最低。
