Lunglmayr G, Stellamor M, Spona J
Wien Klin Wochenschr. 1980 Mar 28;92(7):243-7.
The aim of the present investigation was to assess impotence in elderly men by clinical, endocrinological and psychological examinations. Altogether 17 patients were treated in a double-blind study with placebo or 75 mg mesterolone per day over 8 weeks. The subjects were aged between 45 and 60 years and suffered from impotentia coeundi. No differences in serum LH and testosterone levels were noted between the start and end of therapy. Similarly, serum LH and testosterone levels in these patients did not differ from those in a control group. These results suggest that the "male climacteric" need not necessarily the associated with alterations in hormone parameters. On the other hand, mesterolone therapy resulted in an improvement in potency and other psychosomatic parameters.
本研究的目的是通过临床、内分泌和心理检查来评估老年男性的阳痿情况。在一项双盲研究中，共有17名患者接受了治疗，他们被随机分配接受安慰剂或每天75毫克美睾酮治疗，为期8周。研究对象年龄在45岁至60岁之间，患有性交不能症。治疗开始和结束时，血清促黄体生成素（LH）和睾酮水平没有差异。同样，这些患者的血清LH和睾酮水平与对照组也没有差异。这些结果表明，“男性更年期”不一定与激素参数的改变有关。另一方面，美睾酮治疗使性功能和其他心身参数得到了改善。
