John H
Urologische Klinik, Universitätsspital Zürich.
Ther Umsch. 1998 Jun;55(6):372-6.
Testosterone and dihydrotestosterone play a critical role during embryogenesis of the male genitalia. The development of secondary sex characteristics depends on normal circulating androgen levels. They maintain libido and sexual potency. Before testosterone supplementation men with erectile failure should receive through hormonal investigation. Testosterone is useless in the treatment of erectile problems in men with normal androgen levels. Testosterone can be administered by intramuscular, oral or transdermal routes. Transdermal systems produce serum testosterone levels closely mimicking the diurnal pattern described in healthy young men. In elderly men during long term therapy, prostate specific antigen should be measured regularly to anticipate malignant growth in the prostate.
睾酮和双氢睾酮在男性生殖器胚胎发育过程中起关键作用。第二性征的发育取决于正常的循环雄激素水平。它们维持性欲和性功能。在补充睾酮之前，勃起功能障碍的男性应接受激素检查。睾酮对雄激素水平正常的男性勃起问题治疗无效。睾酮可通过肌肉注射、口服或经皮途径给药。经皮给药系统产生的血清睾酮水平能紧密模拟健康年轻男性的昼夜模式。在老年男性长期治疗期间，应定期测量前列腺特异性抗原，以预测前列腺的恶性生长。
