Tolonen U, Ahonen A, Kallanranta T, Hokkanen E, Koskinen M, Kuikka J
Acta Neurol Scand. 1980 Mar;61(3):137-45. doi: 10.1111/j.1600-0404.1980.tb01476.x.
Quantitative determinations of regional cerebral blood flow (rCBFf, rCBFm) and volume (rCBV), transfer time (rCTT) and fast compartmental weight (Wf) were performed in 34 patients with infarctions of the carotid area by a 133Xe and 99mTc intravenous injection method. The results were compared with clinical signs and electroencephalographic (EEG) findings. A significant difference was found between the lesion side and the control side in all the parameters except rCBV. This difference increased with the severity of the infarction and age of the patients. The difference between the two sides was especially great in the patients with totally occluded internal carotid artery. A slight diaschisis could be observed in the present infarction group. An almost significant reduction on the "normal side" was seen in Wf. In order to assess the reciprocal influence of all the different blood flow parameters, the difference index (DI): Formula: (see text) was calculated, where delta i = the difference between the two sides in one parameter expressed in percent. This proved to be abnormal in 80% of the patients. The atraumatic isotope technique employed offers a good opportunity for the quantitative evaluation of hemodynamics in cerebral infarction and serves as an aid in the diagnosis of infarction.
采用¹³³Xe和⁹⁹ᵐTc静脉注射法，对34例颈动脉区梗死患者进行了局部脑血流量（rCBFf、rCBFm）、脑血容量（rCBV）、转运时间（rCTT）和快速成分重量（Wf）的定量测定。将结果与临床体征和脑电图（EEG）结果进行了比较。除rCBV外，所有参数在病变侧与对照侧之间均存在显著差异。这种差异随着梗死严重程度和患者年龄的增加而增大。在颈内动脉完全闭塞的患者中，两侧差异尤为显著。在本梗死组中可观察到轻微的交叉性小脑神经机能联系不能。在Wf方面，“正常侧”出现了几乎显著的降低。为了评估所有不同血流参数的相互影响，计算了差异指数（DI）：公式：（见原文），其中δi = 一个参数两侧差异的百分比表示。结果表明，80%的患者该指数异常。所采用的无创同位素技术为脑梗死血流动力学的定量评估提供了良好的机会，并有助于梗死的诊断。
