Thomas D J, Zilkha E, Redmond S, Du Boulay G H, Marshall J, Russell R W, Symon L
J Neurol Sci. 1979 Jan;40(1):53-63. doi: 10.1016/0022-510x(79)90008-x.
An intravenous 133Xe clearance technique for measuring cerebral blood flow (CBF) is described. Results obtained compared well with those using the intracarotid 133Xe technique. The reproducibility of the method was checked by repeating measurements within a few hours in 14 patients, when no significant overall change occurred, and after some days in 23 patients when a mean fall in flow of 8% was observed. CBF was measured in 52 control subjects. The mean fast component flow (Ff) was 68.6 ml/100 g/min (SD 11.3). No difference between the two hemispheres was found. Flow was confirmed to be higher anteriorly in the cerebral hemispheres. A significant inverse correlation was found between CBF and age.
本文描述了一种用于测量脑血流量（CBF）的静脉注射133Xe清除技术。所得结果与采用颈内注射133Xe技术的结果相比，吻合度良好。通过在14例患者中于数小时内重复测量来检查该方法的可重复性，此时未观察到显著的总体变化；又在23例患者中于数日后重复测量，此时观察到血流量平均下降了8%。对52名对照受试者进行了CBF测量。平均快速成分血流量（Ff）为68.6 ml/100 g/分钟（标准差11.3）。未发现两个半球之间存在差异。经证实，脑半球前部的血流量更高。发现CBF与年龄之间存在显著的负相关。
