Dworkin B R, Filewich R J, Da Costa J, Eissenberg E, Miller N E
Am J Physiol. 1980 Jul;239(1):H137-41. doi: 10.1152/ajpheart.1980.239.1.H137.
A procedure for cannula construction, surgical implantation, and utilization is presented for recording arterial blood pressure and heart rate from the renal artery of unanesthetized mobile rats. The method involves unilateral nephrectomy, but the animals recover quickly and remain in excellent health. The cannula requies minimal maintenance; it has been used in cardiovascular experiments to make multiple periodic arterial blood pressure recordings. Patency for 2 mo or longer is common.
本文介绍了一种用于记录未麻醉活动大鼠肾动脉血压和心率的插管构建、手术植入及使用方法。该方法包括单侧肾切除术,但动物恢复迅速且健康状况良好。该插管维护需求极小;已用于心血管实验以进行多次定期动脉血压记录。通畅2个月或更长时间很常见。