Ogino H, Matsumura T, Satouchi K, Saito K
Biochim Biophys Acta. 1980 Jun 23;618(3):431-8.
Molecular species of rat liver choline glycerophospholipids were investigated at various stages of development by a gas chromatograph-mass spectrometer system. They were composed mainly by 1,2-diacyglycerophosphocholine and changed with development particularly during the perinatal period.. In the prenatal period, the major species were '32 : 0' (mainly 16 : 0/16 : 0, dipalmitoyl species), '34 : 0' (mainly 16 : 0/18 : 0, palmitoystearoyl speciesY, '34 : 1' (mainly 16 : 0/18 : 1, palmitoyloleoyl species) and '34 : 2' (mainly 16 : 0/18 : 2, palmitoyllinoleoyl speciesY and '32 : 0' decreased rapidly and '34 : 1' increased as the stage proceeded. After birth, however, polyunsaturated species such as '34 : 4' and '38 : 4-6' increased rapidly in contrast to the decrease of '32 : 1, 34 : 1, 36 : 1, and 34 : 0'. Moderate changes were observed in these species during subsequent development.
利用气相色谱-质谱联用系统研究了大鼠肝脏胆碱甘油磷脂的分子种类在不同发育阶段的情况。它们主要由1,2-二酰基甘油磷脂胆碱组成，并随发育过程而变化，尤其是在围产期。在产前阶段，主要种类为“32:0”（主要是16:0/16:0，二棕榈酰种类）、“34:0”（主要是16:0/18:0，棕榈酰硬脂酰种类）、“34:1”（主要是16:0/18:1，棕榈酰油酰种类）和“34:2”（主要是16:0/18:2，棕榈酰亚油酰种类），随着发育阶段的推进，“32:0”迅速减少，“34:1”增加。然而，出生后，与“32:1、34:1、36:1和34:0”的减少形成对比的是，“34:4”和“38:4 - 6”等多不饱和种类迅速增加。在随后的发育过程中，这些种类出现了适度的变化。
