Kapiĭ L P
Biull Eksp Biol Med. 1980 May;89(5):612-4.
Focal myocardial necrosis in cats (Felis domestica) was provoked by means of threefold subcutaneous administrtion of isadrin at a rate of 10 mg bw. Cervicothoracic nodes of the boundary sympathetic trunk normally and experimentally were subjected to morphologic and histometric analysis (after 3 hours, 3--7 days and 2 weeks). The presence of foci of myocardial necrosis was supported by electrocardiography data and histologic examination of the myocardium. Histometric analysis of the cervicothoracic nodes revealed shifts in the microcirculatory channel and in the neurocytic-glial complexes. A correlation was revealed between the time course of electrocardiography data on focal myocardial necrosis and consistently developing time-dependent histopathologic changes in the cervicothoracic nodes which are specific for them in acute metabolic myocardial necroses.
通过以10毫克体重的剂量皮下注射三次异丙肾上腺素,诱发家猫(Felis domestica)的局灶性心肌坏死。对正常和实验状态下的颈胸段交感干淋巴结进行形态学和组织计量学分析(分别在3小时、3 - 7天和2周后)。心电图数据和心肌组织学检查证实了心肌坏死灶的存在。颈胸段淋巴结的组织计量学分析显示微循环通道和神经细胞 - 神经胶质复合体发生了变化。局灶性心肌坏死的心电图数据随时间变化过程与颈胸段淋巴结持续出现的、具有急性代谢性心肌坏死特征的时间依赖性组织病理学变化之间存在相关性。