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[某些蛋白聚糖的红外光谱]

[Infrared spectra of certain proteoglycans].

作者信息

Bychkov S M, Bogatov V N, Kharlamova V N

出版信息

Biull Eksp Biol Med. 1980 Jun;89(6):680-2.

PMID:7397357
Abstract

IR spectra of high-purified potassium salts of hyaluronic acid (HA), non-aggregation fraction of protein-chondroitin-keratan sulfate (PChKS) and heparin fractions containing 3 (H-3) and 4 (H-4) residues of sulfuric acid per dimer of polymer have been measured. An absorption band of 1150 cm-1 has been observed in the spectra of both HA and PChKS but has not been found in the spectra of H-3 and H-4. Observation of this band in the spectra of some heparin preparations indicates that they contain the admixtures of HA, PChKS and other proteoglycans. A previously suggested method for isolation of heparin fractions H-3 and H-4 makes it possible to obtain preparations that do not contain the admixtures of other proteoglycans.

摘要

已测量了高纯度透明质酸(HA)钾盐、蛋白质 - 软骨素 - 角蛋白硫酸盐(PChKS)的非聚集部分以及每二聚体聚合物含有3个(H - 3)和4个(H - 4)硫酸残基的肝素部分的红外光谱。在HA和PChKS的光谱中均观察到1150 cm-1的吸收带,但在H - 3和H - 4的光谱中未发现。在某些肝素制剂的光谱中观察到该吸收带表明它们含有HA、PChKS和其他蛋白聚糖的混合物。先前提出的分离肝素部分H - 3和H - 4的方法使得能够获得不含其他蛋白聚糖混合物的制剂。

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