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对霍奇金病患者的两种细胞系进行的体外研究(作者译)

[In vitro studies on two cell lines from patients with Hodgkin's disease (author's transl)].

作者信息

Hertenstein C, von Witzleben-Wurmb G

出版信息

Blut. 1980 May;40(5):313-24. doi: 10.1007/BF01025586.

Abstract

Two cell lines (Ma,Bi) were established in vitro from pleura effusions from two patients with Hodgkin's disease. After some months the monolayer line Ma spontaneously became nonadherent and proliferated in suspension. Immunological properties, enzyme activities, surface characteristics and chromosomal analyses suggested that the culture Ma is composed of lymphoid cells and macrophages. Line Bi propagated attached to the glass and had properties typical for macrophages only.

摘要

从两名霍奇金病患者的胸腔积液中体外建立了两个细胞系(Ma、Bi)。几个月后,单层细胞系Ma自发地变得不贴壁并在悬浮液中增殖。免疫特性、酶活性、表面特征和染色体分析表明,培养的Ma由淋巴细胞和巨噬细胞组成。细胞系Bi贴壁生长,仅具有巨噬细胞的典型特性。

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