Marshall J R
Clin Obstet Gynecol. 1980 Jun;23(2):453-63. doi: 10.1097/00003081-198006000-00014.
Although pregnancy increases the likelihood that prolactin-producing pituitary tumors will grow, become symptomatic, and need therapy, in selected patients this likeihood is small enough that the presence of the tumor, per se, does not constitute a contraindication to pregnancy. A symptom-free pregnancy is suggested by the presence of a small tumor that is enlarging only very slowly if at all. During pregnancy, expansion of the tumor is associated with symptoms and signs that almost always progress in an orderly fashion and provide adequate warning concerning the enlargement of the tumor. Therapy against the tumor during the pregnancy is effective and does not appear to carry an increased complication rate. Pregnancy in patients with prolactin-producing pituitary tumors should be managed carefully but expectantly.
尽管妊娠会增加分泌催乳素的垂体瘤生长、出现症状并需要治疗的可能性，但在特定患者中，这种可能性小到肿瘤本身并不构成妊娠禁忌。如果存在一个小肿瘤且生长极其缓慢（若有生长的话），则提示可能会有一次无症状的妊娠。在妊娠期间，肿瘤增大与症状和体征相关，这些症状和体征几乎总是以有序的方式进展，并能为肿瘤增大提供充分的警示。妊娠期间针对肿瘤的治疗是有效的，且似乎不会增加并发症发生率。对于患有分泌催乳素垂体瘤的患者，妊娠应谨慎管理，但可抱有期待。
