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胰腺和胆汁分泌物中的乙型肝炎表面抗原

Hepatitis B surface antigen in pancreatic and biliary secretions.

作者信息

Hoefs J C, Renner I G, Askhcavai M, Redeker A G

出版信息

Gastroenterology. 1980 Aug;79(2):191-4.

PMID:7399225
Abstract

Pure pancreatic juice (PPJ) and pure bile (PBJ) were obtained by endoscopic retrograde cannulation of the pancreatic duct and common bile duct in 26 patients with acute (15) and chronic (11) hepatitis B infections and the specimens were tested for HBsAg. HBsAg was detected in PPJ in 8 of 15 patients with acute infections and 3 of 10 with chronic infections. HBsAg was detected in PBJ in 7 of 10 with acute infections and only 2 of 5 with chronic type B infection. Since normal PPJ was shown to be inhibitory to the detection of HBsAg, it is suggested that the HBsAg-positive PPJ represents heavy viral excretion.

摘要

通过内镜逆行插管胰管和胆总管,从26例急(15例)慢性(11例)乙型肝炎感染患者中获取纯胰液(PPJ)和纯胆汁(PBJ),并对标本进行HBsAg检测。在15例急性感染患者中,有8例在PPJ中检测到HBsAg;在10例慢性感染患者中,有3例检测到。在10例急性感染患者中,有7例在PBJ中检测到HBsAg;在5例慢性乙型感染患者中,只有2例检测到。由于正常PPJ被证明对HBsAg检测有抑制作用,提示HBsAg阳性的PPJ代表大量病毒排泄。

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