一种罕见的血型抗原，R1a（罗森伦德）。

A rare blood group antigen, R1a (Rosenlund).

作者信息

Kornstad L

出版信息

Immunol Commun. 1980;9(2):217-23. doi: 10.3109/08820138009065995.

DOI:10.3109/08820138009065995

Abstract

A 'new rare blood group antigen R1a (Rosenlund) is reported. The antigen is present in about 1 in 900 Norwegians. Nine unrelated R1(a+) people were found. Studies of seven families, leading to the discovery of 20 additional R1(a+) people, indicated the antigen is inherited as a Mendelian dominant character. Independent segregation was demonstrated between Rla and the ABO, MNSs, Rh, Lutheran, Duffy and Kidd blood group systems, the ABH secretor genes, and sex. The R1a antigen is inactivated by papain treatment. The corresponding antibody, anti-R1a, has so far been found in three sera that also contain antibodies to other rare blood group antigens.

摘要

据报道，发现了一种“新的罕见血型抗原R1a（罗森隆德型）”。该抗原在大约每900名挪威人中就有1人存在。已发现9名无亲缘关系的R1（a+）个体。对7个家族的研究又发现了另外20名R1（a+）个体，这表明该抗原作为孟德尔显性性状遗传。R1a与ABO、MNSs、Rh、路德、达菲和基德血型系统、ABH分泌型基因以及性别之间表现出独立分离。R1a抗原经木瓜蛋白酶处理后失活。到目前为止，在三份血清中发现了相应的抗体抗R1a，这些血清中还含有针对其他罕见血型抗原的抗体。