[各种静脉注射用人γ球蛋白制剂的免疫学特性、聚集物含量及半衰期]
[Immunologic properties, aggregate content and half-life of various human i.v. gamma globulin preparations].
作者信息
Ring J, Duswald K H, Seifert J, Brendel W
出版信息
Langenbecks Arch Chir. 1976;Suppl:63-7.
PMID:73997
Abstract
Anticomplementary activity, aggregate content, and elimination of i.v. human gamma globulin (HGG). During storage of HGG globulin aggregate formation increases leading to anticomplementary activity. Seventeen patients suffering from postoperative sepsis showed significantly faster elimination rates of HGG than 6 healthy controls, while there was no difference in albumin elimination.
摘要
静脉注射人γ球蛋白（HGG）的抗补体活性、聚集物含量及清除情况。在HGG储存过程中，球蛋白聚集物形成增加，导致抗补体活性增强。17例术后脓毒症患者的HGG清除率显著快于6例健康对照者，而白蛋白清除率无差异。
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[Problems of intravenous gammaglobulin therapy (author's transl)].静脉注射丙种球蛋白治疗的问题（作者译）
Klin Wochenschr. 1980 Aug 15;58(16):797-809. doi: 10.1007/BF01491100.
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