碘帕醇、碘克沙醇和泛影葡胺在犬冠状动脉造影术中的比较。
Comparison of iopamidol, ioxaglate, and diatrizoate during coronary arteriography in dogs.
作者信息
Thomson K R, Evill C A, Fritzsche J, Benness G T
出版信息
Invest Radiol. 1980 May-Jun;15(3):234-41. doi: 10.1097/00004424-198005000-00010.
Iopamidol and ioxaglate are two new contrast media which have an osmolality approximately half that of diatrizoate for the same iodine concentration. These three contrast media were compared with each other and with Hartmann's solution during coronary arteriography in dogs using hemodynamic and electrocardiographic parameters in addition to coronary venous sinus sampling to measure changes in osmolality, electrolyte, and contrast media concentration. Iopamidol and ioxaglate had similar, but less toxic, effects in comparison with diatrizoate. These new contrast media may offer a reduction in the morbidity and mortality of coronary arteriography.
碘帕醇和碘克沙醇是两种新型造影剂，在相同碘浓度下，它们的渗透压约为泛影酸盐的一半。在犬冠状动脉造影过程中，除了通过冠状静脉窦采样测量渗透压、电解质和造影剂浓度的变化外，还使用血流动力学和心电图参数，将这三种造影剂相互比较，并与哈特曼氏溶液进行比较。与泛影酸盐相比，碘帕醇和碘克沙醇具有相似但毒性较小的作用。这些新型造影剂可能会降低冠状动脉造影的发病率和死亡率。
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