Rowland L P
J Neurol Neurosurg Psychiatry. 1980 Jul;43(7):644-59. doi: 10.1136/jnnp.43.7.644.
Clinicians treating patients with myasthenia gravis must choose cholinergic drugs, corticosteroids, immunosuppressive drugs, thymectomy, or plasmapheresis. Clinicians must decide the sequence or combination of these therapies and when to deem lack of improvement a sign for a different therapeutic approach. Because controlled trials have not been done to evaluate therapies that may require months or years before benefit is evident, controversy abounds.
治疗重症肌无力患者的临床医生必须选择胆碱能药物、皮质类固醇、免疫抑制药物、胸腺切除术或血浆置换。临床医生必须决定这些治疗方法的顺序或组合,以及何时将缺乏改善视为采用不同治疗方法的指征。由于尚未进行对照试验来评估可能需要数月或数年才能显效的治疗方法,因此争议颇多。